This site uses cookies.
Some of these cookies are essential to the operation of the site,
while others help to improve your experience by providing insights into how the site is being used.
For more information, please see the ProZ.com privacy policy.
Dec 27, 2016 (posted viaProZ.com): I am translating a series of lectures about the treatment of insomnia, it is really helpful for me, I have suffered from insomnia with anxiety for many years....more »
This person has a SecurePRO™ card. Because this person is not a ProZ.com Plus subscriber, to view his or her SecurePRO™ card you must be a ProZ.com Business member or Plus subscriber.
Access to Blue Board comments is restricted for non-members. Click the outsourcer name to view the Blue Board record and see options for gaining access to this information.
English英语译成Chinese汉语: Medical translation sample General field: 医学 Detailed field: 医疗：医药
原文文本 - English英语 Antibody-mediated immunotherapy
Exploration of immunotherapy for the treatment of malignancies using polyclonal Ab preparations began in the 1950s. Major advances in Ab-mediated immunotherapy emerged in 1975 when techniques for producing mAbs were developed, making it feasible to produce large quantities of identical Abs directed against specific antigens (Ags). The first cancer therapeutic Abs studied were of murine, rabbit, or rat origins obtained following immunization of the animal with an antigenic preparation. Patients often generated humoral immune response against these therapeutic Abs referred to as human anti-mouse Ab (HAMA) or human anti-rabbit/rat Ab (HARA), which blocked the efficacy of the therapeutic Ab by prematurely clearing the Ab, thus, limiting the possibilities for effective antitumor response. The host Ab responses were mainly immune complex-related adverse events such as serum sickness and anaphylaxis. For example, HAMA rates as high as 41% have been observed in previously untreated NHL patients receiving anti-B1 Ab. In addition to HARA and HAMA, murine, rabbit, and rat Abs are poorly able to recruit human effector functions such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), which facilitate the destruction of a tumor cell. To overcome obstacles inherent in the first generation Abs, hybrids composed of mouse or primate Ab regions linked with a human backbone were constructed. These are referred to as chimeric, humanized or primatized Abs, depending on the exact Ab structure. For instance, humanized Ab is a human Ab containing the complementarity- determining regions (CDR) of non-human origin and human constant regions. These genetically engineered Abs are potent inducers of ADCC and CDC and also have enhanced half-life which contributes to their efficacy. For instance, the half-life of the chimeric anti-CD20 Ab, rituximab, is 76 h after a single infusion and 206 h after four infusions, compared with 28 h for the murine counterpart, ibritumomab. The incidence of immune responses with secondgeneration Abs is also significantly lower than that seen with cross-species Abs. Examples of mAbs clinically used in the treatment of cancers are edrecolomab (Panorexs), which was approved in Europe in 1994 and trastuzumab (Herceptins) that was approved in the US in 1998. These mAbs, in combination with chemotherapy, are effectively used in the treatment of patients with colorectal and breast cancer, respectively. In February 2004, the food and drug administration (FDA) approved bevacizumab, antivascular endothelial growth factor (VEGF) mAb as a first-lime therapy for metastatic colorectal cancer, which is the first therapeutic to target tumor angiogenesis.
原文文本 - English英语 Furunculosis
Furunculosis is an infection of a hair follicle in the lateral part of the external canal - usually caused by Staphylococcus aureus.
16 It causes unilateral pain that is worse on eating (due to the proximity of the temporomandibular joint) and on movement of the pinna.
Since it can obstruct the ear canal, patients can have hearing loss.
The furuncle may discharge pus.
16
Otoscopy reveals a red, localised pustule in the canal.
It is best treated with a course of oral flucloxacillin (or erythromycin in penicillin sensitive patients).
An ear wick can ease pain and reduce swelling.
If these measures fail the patient may need referral for further management, for example incision and drainage.
Master of Pharmacology,
Bachelor of Clinical Medicine
Final
Proofreader of NCCN Guidelines – Chinese Edition
Since 2003, I have performed the following
tasks on a regular basis:
· Worked as a freelance English
to Chinese translator/proofreader.
· Translated a wide range of medically-related
documents, including:
o Clinical trial proposals
o Patient informed consent
documents
o Pharmacology reports
o Pharmaceutical package inserts
o Medical instruments manuals
In 2010, I began assisting Chinese patients
travelling to the United States for medical treatment. Assisting patients
included the regular translation of English medical records, computed
tomography (CT), magnetic resonance imaging (MRI), positron emission tomography
(PET) scans and pathology reports. To date, over 600 patients have made use of
my translation skills
COMPLETED PROJECTS
1. Final proofreader for the simplified
Chinese version of the annual National Comprehensive Cancer Network’s (NCCN) Clinical
Practice Guidelines in Oncology from 2014 up to now. The information contained
in each sentence, figure and chart was validated and verified. Any missing
information and/or errors were corrected.
2. Translator and editor of clinical
trial protocols for informed consents of clinical trials conducted in China
between U.S. pharmaceutical companies and Chinese hospitals.
3. Translator of medical records,
CT and MRI scans as well as immunohistochemistry (IHC) and pathology reports
from Chinese to English for Chinese patients seeking additional medical
treatment in the U.S. Translated reports and findings from U.S. experts to
Chinese.
4. Translator of medical
instrument manuals and pharmaceutical package inserts.
加入会员日期： Dec '11
专长